Name | mulberroside A |
Synonyms | mulberroside A 2,5'-Dihydroxy-4,3'-bis(β-D-glucopyranosyloxy)-trans-stilbene 2,5'-Dihydroxy-4,3'-bis(beta-D-glucopyranosyloxy)-trans-stilbene b-D-Glucopyranoside,3-[(1E)-2-[4-(b-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl β-D-Glucopyranoside, 3-[(1E)-2-[4-(β-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl 3-{(E)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl}-5-hydroxyphenyl beta-D-glucopyranoside 2-(4-hydroxy-1,3-thiazol-3-ium-3-yl)ethyl [2-(octadecylcarbamoyloxymethyl)oxolan-2-yl]methyl phosphate beta-D-Glucopyranoside 3-[(1E)-2-[4-(beta-D-glucopyranosyloxy)-2-hydroxyphenyl]ethenyl]-5-hydroxyphenyl |
CAS | 102841-42-9 |
InChI | InChI=1/C26H32O14/c27-9-17-19(31)21(33)23(35)25(39-17)37-14-4-3-12(16(30)8-14)2-1-11-5-13(29)7-15(6-11)38-26-24(36)22(34)20(32)18(10-28)40-26/h1-8,17-36H,9-10H2/b2-1+/t17-,18-,19-,20-,21+,22+,23-,24-,25-,26-/m1/s1 |
Molecular Formula | C26H32O14 |
Molar Mass | 568.52 |
Density | 1.654 |
Melting Point | 235-236o C |
Boling Point | 954.7±65.0 °C(Predicted) |
Specific Rotation(α) | -78 (c, 0.88 in MeOH) |
Flash Point | 531℃ |
Solubility | DMSO : ≥ 100 mg/mL (175.90 mM) |
Vapor Presure | 0mmHg at 25°C |
Appearance | Powder |
Color | White to Off-White |
pKa | 9.03±0.40(Predicted) |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Refractive Index | 1.741 |
MDL | MFCD16294844 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Mori white skin. |
In vivo study | Mulberroside A (10, 20, and 40 mg/kg) decreases serum uric acid levels and increases urinary urate excretion and fractional excretion of uric acid in hyperuricemic micem. Animal Model: Male Kun-Ming mice (20±2 g) Dosage: 5, 10, 20, and 40 mg/kg; the dose volume 10 mL/kg body weight Administration: Orally initiated at 9:00 a.m. Result: 10, 20, and 40 mg/kg significantly increased urinary urate excretion in 24 h, resulting in a remarkable elevation of fractional excretion of uric acid (FEUA), and the highest dose completely reversed FEUA alteration of hyperuricemic mice to normal. |
HS Code | 29389090 |
Reference Show more | 1. Zhao Tingting, Wei Hua, Chen Liangmian, et al. Comparative Study on HPLC Fingerprints of Different Medicinal Parts of Mulberry [J]. Chinese Journal of Pharmacy, 2017(07):45-51. 2. [IF = 3.571] Ya-Nan Jia et al."Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs." J Agr Food Chem. 2019;67(19):5521-5529 |